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Hierarchical differentiation competence in response to retinoic acid ensures stem cell maintenance during mouse spermatogenesis

Stem cells ensure tissue homeostasis through the production of differentiating and self-renewing progeny. In some tissues, this is achieved by the function of a definitive stem cell niche. However, the mechanisms that operate in mouse spermatogenesis are unknown because undifferentiated spermatogoni...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Ikami, Kanako, Tokue, Moe, Sugimoto, Ryo, Noda, Chiyo, Kobayashi, Satoru, Hara, Kenshiro, Yoshida, Shosei
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419276/
https://ncbi.nlm.nih.gov/pubmed/25858458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.118695
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