Single-cell microRNA-mRNA co-sequencing reveals non-genetic heterogeneity and mechanisms of microRNA regulation

Measuring multiple omics profiles from the same single cell opens up the opportunity to decode molecular regulation that underlies intercellular heterogeneity in development and disease. Here, we present co-sequencing of microRNAs and mRNAs in the same single cell using a half-cell genomics approach...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wang, Nayi, Zheng, Ji, Chen, Zhuo, Liu, Yang, Dura, Burak, Kwak, Minsuk, Xavier-Ferrucio, Juliana, Lu, Yi-Chien, Zhang, Miaomiao, Roden, Christine, Cheng, Jijun, Krause, Diane S., Ding, Ye, Fan, Rong, Lu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327095/
https://ncbi.nlm.nih.gov/pubmed/30626865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07981-6
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