Single-cell microRNA-mRNA co-sequencing reveals non-genetic heterogeneity and mechanisms of microRNA regulation

Measuring multiple omics profiles from the same single cell opens up the opportunity to decode molecular regulation that underlies intercellular heterogeneity in development and disease. Here, we present co-sequencing of microRNAs and mRNAs in the same single cell using a half-cell genomics approach...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Wang, Nayi, Zheng, Ji, Chen, Zhuo, Liu, Yang, Dura, Burak, Kwak, Minsuk, Xavier-Ferrucio, Juliana, Lu, Yi-Chien, Zhang, Miaomiao, Roden, Christine, Cheng, Jijun, Krause, Diane S., Ding, Ye, Fan, Rong, Lu, Jun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327095/
https://ncbi.nlm.nih.gov/pubmed/30626865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07981-6
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