Genome-wide DNA hypermethylation and homocysteine increase a risk for myopia

AIM: To test for the association between genome-wide methylation and myopia in human and mice. METHODS: Long interspersed nucleotide element 1 (LINE-1) methylation levels were used to surrogate genome-wide methylation level. We first tested for the association between high myopia (<-6 D) and LINE...

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Bibliografski detalji
Izdano u:Int J Ophthalmol
Glavni autori: Hsi, Edward, Wang, Yung-Song, Huang, Chia-Wei, Yu, Ming-Lung, Juo, Suh-Hang Hank, Liang, Chung-Ling
Format: Artigo
Jezik:Inglês
Izdano: International Journal of Ophthalmology Press 2019
Teme:
Basic Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326929/
https://ncbi.nlm.nih.gov/pubmed/30662838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2019.01.06
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