Imaging Pulmonary Foreign Body Reaction Using [(125)I]iodo-DPA-713 SPECT/CT in Mice

PURPOSE: Foreign body reactions elicit granulomatous inflammation composed of reactive macrophages. We hypothesized that [(125)I]iodo-DPA-713 single-photon emission computed tomography (SPECT), a low-molecular-weight pyrazolopyrimidine ligand selectively trapped by phagocytes, could be used to detec...

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Udgivet i:Mol Imaging Biol
Main Authors: Sanchez-Bautista, Julian, Foss, Catherine A., Ordonez, Alvaro A., Klunk, Mariah H., Jain, Sanjay K.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326897/
https://ncbi.nlm.nih.gov/pubmed/29987615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-018-1249-0
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