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Method for quantifying oxidized methionines and application to HIV-1 Env

Recombinantly expressed proteins are susceptible to oxidation during expression, purification, storage and analysis; the residue most susceptible to oxidation is methionine. Methionine oxidation can be overestimated using current quantitative analysis methods because oxidation can occur during sampl...

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Bibliografske podrobnosti
izdano v:J Am Soc Mass Spectrom
Main Authors: Shipman, Joshua T., Go, Eden P., Desaire, Heather
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326892/
https://ncbi.nlm.nih.gov/pubmed/29987661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-018-2010-2
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