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Treatment effect on ordinal functional outcome using piecewise multistate Markov model with unobservable baseline: An application to the modified Rankin Scale

In clinical trials, longitudinally assessed ordinal outcomes are commonly dichotomized and only the final measure is used for primary analysis, partly for ease of clinical interpretation. Dichotomization of the ordinal scale and failure to utilize the repeated measures can reduce statistical power....

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Detalhes bibliográficos
Publicado no:J Biopharm Stat
Principais autores: Cassarly, Christy, Martin, Renee’ H., Chimowitz, Marc, Peña, Edsel A., Ramakrishnan, Viswanathan, Palesch, Yuko Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326882/
https://ncbi.nlm.nih.gov/pubmed/29985739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2018.1489404
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