Regression Analysis of Ordinal Stroke Clinical Trial Outcomes: An Application to the NINDS t-PA Trial

BACKGROUND: The modified Rankin scale (mRS) is the most common functional outcome assessed in stroke trials. The proportional odds model is commonly used to analyze this ordinal outcome but it requires a restrictive assumption that a single odds ratio applies across the entire outcome scale. AIMS: T...

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Udgivet i:Int J Stroke
Main Authors: DeSantis, Stacia M, Lazaridis, Christos, Palesch, Yuko, Ramakrishnan, Ramesh
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042689/
https://ncbi.nlm.nih.gov/pubmed/23803174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ijs.12052
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