Adrenal tissue-specific deletion of TASK channels causes aldosterone-driven Angiotensin II-independent hypertension.

The renin-angiotensin system tightly controls aldosterone synthesis. Dysregulation is evident in hypertension (primary aldosteronism, low-renin and resistant hypertension), but also can exist in normotension. Whether chronic, mild aldosterone autonomy can elicit hypertension remains untested. Previo...

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Gepubliceerd in:Hypertension
Hoofdauteurs: Guagliardo, Nick A., Yao, Junlan, Stipes, Eric J., Cechova, Sylvia, Le, Thu H., Bayliss, Douglas A., Breault, David T., Barrett, Paula Q.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326871/
https://ncbi.nlm.nih.gov/pubmed/30580687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.11962
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