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Melatonin prevents deterioration in quality by preserving epigenetic modifications of porcine oocytes after prolonged culture

Prolonged culture of metaphase II oocytes is an in vitro aging process that compromises oocyte quality. We tested whether melatonin preserves epigenetic modifications in oocytes after prolonged culture. The porcine oocytes were maturated in vitro for 44 h, and then metaphase II oocytes were continuo...

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Библиографические подробности
Опубликовано в: :Aging (Albany NY)
Главные авторы: Nie, Junyu, Xiao, Peng, Wang, Xuefang, Yang, Xiaogan, Xu, Huiyan, Lu, Kehuan, Lu, Shengsheng, Liang, Xingwei
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326688/
https://ncbi.nlm.nih.gov/pubmed/30530915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101680
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