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RNA-Seq Profiling of Intact and Enucleated Oocyte SCNT Embryos Reveals the Role of Pig Oocyte Nucleus in Somatic Reprogramming

The specific molecular mechanisms involved in somatic reprogramming remain unidentified. Removal of the oocyte genome is one of the primary causes of developmental failure in cloned embryos, whereas intact oocyte shows stronger reprogramming capability than enucleated oocyte. To identify the reason...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bai, Lin, Li, Mengqi, Sun, Junli, Yang, Xiaogan, Lu, Yangqing, Lu, Shengsheng, Lu, Kehuan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829232/
https://ncbi.nlm.nih.gov/pubmed/27070804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153093
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