ΔNp63 promotes IGF1 signalling through IRS1 in squamous cell carcinoma

Accumulating evidence has proved that deregulation of ΔNp63 expression plays an oncogenic role in head and neck squamous cell carcinomas (HNSCCs). Besides p63, the type 1-insulin-like growth factor (IGF) signalling pathway has been implicated in HNSCC development and progression. Most insulin/IGF1 s...

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Detalles Bibliográficos
Publicado en:Aging (Albany NY)
Autores principales: Frezza, Valentina, Fierro, Claudia, Gatti, Elena, Peschiaroli, Angelo, Lena, Anna Maria, Petruzzelli, Margherita Annicchiarico, Candi, Eleonora, Anemona, Lucia, Mauriello, Alessandro, Pelicci, Pier Giuseppe, Melino, Gerry, Bernassola, Francesca
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326668/
https://ncbi.nlm.nih.gov/pubmed/30594912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101725
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