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ΔNp63 promotes IGF1 signalling through IRS1 in squamous cell carcinoma

Accumulating evidence has proved that deregulation of ΔNp63 expression plays an oncogenic role in head and neck squamous cell carcinomas (HNSCCs). Besides p63, the type 1-insulin-like growth factor (IGF) signalling pathway has been implicated in HNSCC development and progression. Most insulin/IGF1 s...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Frezza, Valentina, Fierro, Claudia, Gatti, Elena, Peschiaroli, Angelo, Lena, Anna Maria, Petruzzelli, Margherita Annicchiarico, Candi, Eleonora, Anemona, Lucia, Mauriello, Alessandro, Pelicci, Pier Giuseppe, Melino, Gerry, Bernassola, Francesca
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326668/
https://ncbi.nlm.nih.gov/pubmed/30594912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101725
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