ΔNp63 promotes IGF1 signalling through IRS1 in squamous cell carcinoma

Accumulating evidence has proved that deregulation of ΔNp63 expression plays an oncogenic role in head and neck squamous cell carcinomas (HNSCCs). Besides p63, the type 1-insulin-like growth factor (IGF) signalling pathway has been implicated in HNSCC development and progression. Most insulin/IGF1 s...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Frezza, Valentina, Fierro, Claudia, Gatti, Elena, Peschiaroli, Angelo, Lena, Anna Maria, Petruzzelli, Margherita Annicchiarico, Candi, Eleonora, Anemona, Lucia, Mauriello, Alessandro, Pelicci, Pier Giuseppe, Melino, Gerry, Bernassola, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326668/
https://ncbi.nlm.nih.gov/pubmed/30594912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101725
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