Carregant...
The Human IL-7 Receptor Gene: Deletions, Polymorphisms and Mutations
Most T cell subsets depend on IL-7 for survival. IL-7 binds to IL-7Rα and γc, initiating the signaling cascade. Deletion of IL-7Ra in humans has, for some time, been known to cause severe combined immunodeficiency. More recently, polymorphisms in IL-7R have been shown be a risk factor for a number o...
Guardat en:
| Publicat a: | Semin Immunol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6326362/ https://ncbi.nlm.nih.gov/pubmed/22425228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2012.02.007 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|