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FGF8 induces therapy resistance in neoadjuvantly radiated rectal cancer

PURPOSE: Therapy response to neoadjuvant radiochemotherapy (nRCT) of locally advanced rectal cancer varies widely so that markers predicting response are urgently needed. Fibroblast growth factor (FGF) and FGF receptor (FGFR) signaling is involved in pro-survival signaling and thereby may result in...

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Vydáno v:J Cancer Res Clin Oncol
Hlavní autoři: Harpain, Felix, Ahmed, Mohamed A., Hudec, Xenia, Timelthaler, Gerald, Jomrich, Gerd, Müllauer, Leonhard, Selzer, Edgar, Dörr, Wolfgang, Bergmann, Michael, Holzmann, Klaus, Grasl-Kraupp, Bettina, Grusch, Michael, Berger, Walter, Marian, Brigitte, Silberhumer, Gerd R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326005/
https://ncbi.nlm.nih.gov/pubmed/30276721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-018-2757-7
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