FGF8 induces therapy resistance in neoadjuvantly radiated rectal cancer

PURPOSE: Therapy response to neoadjuvant radiochemotherapy (nRCT) of locally advanced rectal cancer varies widely so that markers predicting response are urgently needed. Fibroblast growth factor (FGF) and FGF receptor (FGFR) signaling is involved in pro-survival signaling and thereby may result in...

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Pubblicato in:J Cancer Res Clin Oncol
Autori principali: Harpain, Felix, Ahmed, Mohamed A., Hudec, Xenia, Timelthaler, Gerald, Jomrich, Gerd, Müllauer, Leonhard, Selzer, Edgar, Dörr, Wolfgang, Bergmann, Michael, Holzmann, Klaus, Grasl-Kraupp, Bettina, Grusch, Michael, Berger, Walter, Marian, Brigitte, Silberhumer, Gerd R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2018
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Original Article – Cancer Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326005/
https://ncbi.nlm.nih.gov/pubmed/30276721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-018-2757-7
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