CLIC4/Arf6 Pathway: A New Lead in BMPRII Inhibition in Pulmonary Hypertension

RATIONALE: Increased expression of CLIC4 (chloride intracellular channel 4) is a feature of endothelial dysfunction in pulmonary arterial hypertension, but its role in disease pathology is not fully understood. OBJECTIVE: To identify CLIC4 effectors and evaluate strategies targeting CLIC4 signaling...

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Vydáno v:Circ Res
Hlavní autoři: Abdul-Salam, Vahitha B., Russomanno, Giusy, Chien-Nien, Chen, Mahomed, Abdul S., Yates, Luke A., Wilkins, Martin R., Zhao, Lan, Gierula, Magdalena, Dubois, Oliver, Schaeper, Ute, Endruschat, Jens, Wojciak-Stothard, Beata
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2019
Témata:
Molecular Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325770/
https://ncbi.nlm.nih.gov/pubmed/30582444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.313705
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