Overexpression of CD59 inhibits apoptosis of T-acute lymphoblastic leukemia via AKT/Notch1 signaling pathway

BACKGROUND: T-acute lymphoblastic leukemia (T-ALL) was a hematological malignancy characterized by the accumulation of immature T cells in bone marrow and peripheral blood. In this study, we tried to explore the physiological role of CD59 in T-ALL. METHODS: In this study, we collected the bone marro...

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Dades bibliogràfiques
Publicat a:Cancer Cell Int
Autors principals: Jia, Yanfei, Qi, Yan, Wang, Yunshan, Ma, Xiaoli, Xu, Yihui, Wang, Jun, Zhang, Xiaoqian, Gao, Meihua, Cong, Beibei, Han, Shuyi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Primary Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325688/
https://ncbi.nlm.nih.gov/pubmed/30636930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-018-0714-9
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