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Selective Small Molecule Recognition of RNA Base Pairs

Many types of RNAs exist in the human transcriptome, yet only the bacterial ribosome has been exploited as a small molecule drug target. Aside from rRNA, other cellular RNAs such as noncoding RNAs have primarily secondary structure and limited tertiary structure. Within these secondary structures of...

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Vydáno v:ACS Comb Sci
Hlavní autoři: Haniff, Hafeez S., Graves, Amanda, Disney, Matthew D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325646/
https://ncbi.nlm.nih.gov/pubmed/29966095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.8b00049
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