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Structure Revision of Poecillastrin C and the Absolute Configuration of the β‑Hydroxyaspartic Acid Residue

The planar structure of poecillastrin C (1) was revised through selective reduction of the ester carbon. The absolute configuration of the β-hydroxyaspartic acid (OHAsp) residue was determined to be D-threo by Marfey’s analysis. The acid hydrolysate of the reduction product of 1 liberated (2R,3R)-2-...

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Vydáno v:Org Lett
Hlavní autoři: Irie, Raku, Takada, Kentaro, Ise, Yuji, Ohtsuka, Susumu, Okada, Shigeru, Gustafson, Kirk R., Matsunaga, Shigeki
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325643/
https://ncbi.nlm.nih.gov/pubmed/28956931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b02835
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