Sensitization of keloid fibroblasts by quercetin through the PI3K/Akt pathway is dependent on regulation of HIF-1α

Keloids are raised, red, hard and irregular tumors that are prone to extend beyond the wound borders. Surgical excision is not sufficient to eradicate a keloid. Adjuvant therapy with radiation is a recommended treatment that reportedly achieves improved efficacy. However, radiation does not only kil...

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Udgivet i:Am J Transl Res
Main Authors: Si, Lou-Bin, Zhang, Ming-Zi, Han, Qin, Huang, Jian-Nan, Long, Xiao, Long, Fei, Zhao, Robert Chun-Hua, Huang, Jiu-Zuo, Liu, Zhi-Fei, Zhao, Ru, Zhang, Hai-Lin, Wang, Xiao-Jun
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2018
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325497/
https://ncbi.nlm.nih.gov/pubmed/30662665
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