Daptomycin Resistance and Tolerance Due to Loss of Function in Staphylococcus aureus dsp1 and asp23

Lipopeptide daptomycin is a last-line cell-membrane-targeting antibiotic to treat multidrug-resistant Staphylococcus aureus. Alarmingly, daptomycin-resistant S. aureus isolates have emerged. The mechanisms underlying daptomycin resistance are diverse and share similarities with resistances to cation...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Barros, Elaine M., Martin, Melissa J., Selleck, Elizabeth M., Lebreton, François, Sampaio, Jorge Luiz M., Gilmore, Michael S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325204/
https://ncbi.nlm.nih.gov/pubmed/30397055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01542-18
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