Blockade of CTLA-4 and Tim-3 pathways induces fetal loss with altered cytokine profiles by decidual CD4(+)T cells

The single and/or combination use of immune checkpoint blockade therapies in human infectious diseases and cancer are rapidly expanding. Despite early efforts, substantial uncertainty remains about the safety and efficacy of immune checkpoint blockade in some populations. Cytotoxic T-lymphocyte-asso...

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Foilsithe in:Cell Death Dis
Main Authors: Wang, Songcun, Chen, Chunqin, Li, Mengdie, Qian, Jinfeng, Sun, Fengyun, Li, Yunyun, Yu, Min, Wang, Mingyan, Zang, Xingxing, Zhu, Rui, Li, Dajin, Du, Meirong
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325160/
https://ncbi.nlm.nih.gov/pubmed/30622243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1251-0
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