Multiparametric magnetic resonance imaging in the assessment of anti-EGFRvIII chimeric antigen receptor T cell therapy in patients with recurrent glioblastoma

EGFRvIII targeted chimeric antigen receptor T (CAR-T) cell therapy has recently been reported for treating glioblastomas (GBMs); however, physiology-based MRI parameters have not been evaluated in this setting. Ten patients underwent multiparametric MRI at baseline, 1, 2 and 3 months after CAR-T the...

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Dades bibliogràfiques
Publicat a:Br J Cancer
Autors principals: Wang, Sumei, O’Rourke, Donald M., Chawla, Sanjeev, Verma, Gaurav, Nasrallah, MacLean P., Morrissette, Jennifer J. D., Plesa, Gabriela, June, Carl H., Brem, Steven, Maloney, Eileen, Desai, Arati, Wolf, Ronald L., Poptani, Harish, Mohan, Suyash
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Brief Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325110/
https://ncbi.nlm.nih.gov/pubmed/30478409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0342-0
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