Multiparametric magnetic resonance imaging in the assessment of anti-EGFRvIII chimeric antigen receptor T cell therapy in patients with recurrent glioblastoma

EGFRvIII targeted chimeric antigen receptor T (CAR-T) cell therapy has recently been reported for treating glioblastomas (GBMs); however, physiology-based MRI parameters have not been evaluated in this setting. Ten patients underwent multiparametric MRI at baseline, 1, 2 and 3 months after CAR-T the...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Wang, Sumei, O’Rourke, Donald M., Chawla, Sanjeev, Verma, Gaurav, Nasrallah, MacLean P., Morrissette, Jennifer J. D., Plesa, Gabriela, June, Carl H., Brem, Steven, Maloney, Eileen, Desai, Arati, Wolf, Ronald L., Poptani, Harish, Mohan, Suyash
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325110/
https://ncbi.nlm.nih.gov/pubmed/30478409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0342-0
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