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Aspirin ameliorates experimental autoimmune encephalomyelitis through interleukin-11–mediated protection of regulatory T cells

Multiple sclerosis (MS) is a human disease that results from autoimmune T cells targeting myelin protein that is expressed within the central nervous system. In MS, the number of FoxP3-expressing regulatory T cells (T(regs)) is reduced, which facilitates the activation of autoreactive T cells. Becau...

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Bibliographic Details
Published in:Sci Signal
Main Authors: Mondal, Susanta, Jana, Malabendu, Dasarathi, Sridevi, Roy, Avik, Pahan, Kalipada
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325078/
https://ncbi.nlm.nih.gov/pubmed/30482850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aar8278
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