Persistent Attenuation of Nicotine Self-Administration in Rats by Co-administration of Chronic Nicotine Infusion with the Dopamine D(1) Receptor Antagonist SCH-23390 or the Serotonin 5-HT(2C) Agonist Lorcaserin

Tobacco addiction each year causes millions of deaths worldwide. Brain nicotinic acetylcholine receptors have been shown to be central to tobacco addiction. Nicotine replacement therapy aids tobacco cessation, but the success rate is still far too low. This may in part be due to the fact that neuron...

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Detalhes bibliográficos
Publicado no:Pharmacol Biochem Behav
Main Authors: DiPalma, Devon, Rezvani, Amir H., Willette, Blair, Wells, Corinne, Slade, Susan, Hall, Brandon J., Levin, Edward D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325022/
https://ncbi.nlm.nih.gov/pubmed/30419272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2018.11.002
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