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Ketanserin, a 5-HT(2) receptor antagonist, decreases nicotine self-administration in rats

Nicotine intake constitutes a principal mechanism for tobacco addiction. In addition to primary effects on nicotinic acetylcholine receptors, nicotine has cascading effects, which may underlie its neurobehavioral actions. Nicotine induces serotonin (5-HT) release, which has not classically been thou...

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Detalhes bibliográficos
Main Authors: Levin, Edward D., Slade, Susan, Johnson, Michael, Petro, Ann, Horton, Kofi, Williams, Paul, Rezvani, Amir H., Rose, Jed E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638587/
https://ncbi.nlm.nih.gov/pubmed/18950618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2008.10.016
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