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Dual oxidase 1(Duox1) regulates primary B cell function under the influence of IL-4 through BCR-mediated generation of hydrogen peroxide

Engagement of the B cell receptor (BCR) with antigens triggers signaling pathways for commitment of B-lymphocyte responses that can be regulated, in part, by reactive oxygen species (ROS). To investigate the functional relevance of ROS produced in primary B cells, we focused on the role of the hydro...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Sugamata, Ryuichi, Donko, Agnes, Murakami, Yousuke, Boudreau, Howard, Qi, Chen-Feng, Kwon, Jaeyul, Leto, Thomas L.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324942/
https://ncbi.nlm.nih.gov/pubmed/30559322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601395
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