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KLHL5 knockdown increases cellular sensitivity to anticancer drugs

KLHL family genes are noted for their involvement in the E3 ligase ubiquitination pathway through binding with Cullin-3 (CUL3) resulting in degradation of specific binding partners. KLHLs are thus intriguing genes for cancer as they can directly influence the degradation of therapeutically relevant...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Schleifer, Robert J., Li, Shuchun, Nechtman, Wyatt, Miller, Eric, Bai, Shan, Sharma, Ashok, She, Jin-Xiong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324770/
https://ncbi.nlm.nih.gov/pubmed/30647843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26462
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