Method development and validation of ursodiol and its major metabolites in human plasma by HPLC-tandem mass spectrometry

BACKGROUND: Ursodeoxycholic acid (UDCA) and its metabolites tauroursodeoxycholic acid (TUDCA) and glycoursodeoxycholic acid (GUDCA) have been the subject of several pharmacological studies. The objective of this study was to develop an innovative method of quantification by HPL-tandem mass spectrome...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Pharmacol
Egile Nagusiak: Pinto, Márcio Cardoso, Berton, Danilo Chorfi, de Oliveira, Alexandre Cavenatti, Lazaro, Carolina Martins, Carandina, Silvana Aparecida Calafatti
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove Medical Press 2019
Gaiak:
Methodology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324612/
https://ncbi.nlm.nih.gov/pubmed/30655708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S187519
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