Effect of Levocarnitine vs Placebo as an Adjunctive Treatment for Septic Shock: The Rapid Administration of Carnitine in Sepsis (RACE) Randomized Clinical Trial

IMPORTANCE: Sepsis induces profound metabolic derangements, while exogenous levocarnitine mitigates metabolic dysfunction by enhancing glucose and lactate oxidation and increasing fatty acid shuttling. Previous trials in sepsis suggest beneficial effects of levocarnitine on patient-centered outcomes...

詳細記述

保存先:
書誌詳細
出版年:JAMA Netw Open
主要な著者: Jones, Alan E., Puskarich, Michael A., Shapiro, Nathan I., Guirgis, Faheem W., Runyon, Michael, Adams, Jason Y., Sherwin, Robert, Arnold, Ryan, Roberts, Brian W., Kurz, Michael C., Wang, Henry E., Kline, Jeffrey A., Courtney, D. Mark, Trzeciak, Stephen, Sterling, Sarah A., Nandi, Utsav, Patki, Deepti, Viele, Kert
フォーマット: Artigo
言語:Inglês
出版事項: American Medical Association 2018
主題:
Original Investigation
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324339/
https://ncbi.nlm.nih.gov/pubmed/30646314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2018.6076
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