Improving power of association tests using multiple sets of imputed genotypes from distributed reference panels

The accuracy of genotype imputation depends upon two factors: the sample size of the reference panel and the genetic similarity between the reference panel and the target samples. When multiple reference panels are not consented to combine together, it is unclear how to combine the imputation result...

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Bibliographic Details
Published in:Genet Epidemiol
Main Authors: Zhou, Wei, Fritsche, Lars G., Das, Sayantan, Zhang, He, Nielsen, Jonas B., Holmen, Oddgeir L., Chen, Jin, Lin, Maoxuan, Elvestad, Maiken B., Hveem, Kristian, Abecasis, Goncalo R., Kang, Hyun Min, Willer, Cristen J.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324190/
https://ncbi.nlm.nih.gov/pubmed/28861891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22067
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