Increased neutrophil extracellular traps activate NLRP3 and inflammatory macrophages in adult-onset Still’s disease

BACKGROUND: Adult-onset Still’s disease (AOSD) is a systemic inflammatory disease characterized by neutrophilia and NLRP3 inflammasome and macrophage activation. We investigated the role of neutrophil extracellular traps (NETs) in the pathogenesis of AOSD, and explored the effect of NETs on activati...

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Vydáno v:Arthritis Res Ther
Hlavní autoři: Hu, Qiongyi, Shi, Hui, Zeng, Ting, Liu, Honglei, Su, Yutong, Cheng, Xiaobing, Ye, Junna, Yin, Yufeng, Liu, Mengru, Zheng, Hui, Wu, Xinyao, Chi, Huihui, Zhou, Zhuochao, Jia, Jinchao, Sun, Yue, Teng, Jialin, Yang, Chengde
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323819/
https://ncbi.nlm.nih.gov/pubmed/30616678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1800-z
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