Increased neutrophil extracellular traps activate NLRP3 and inflammatory macrophages in adult-onset Still’s disease

BACKGROUND: Adult-onset Still’s disease (AOSD) is a systemic inflammatory disease characterized by neutrophilia and NLRP3 inflammasome and macrophage activation. We investigated the role of neutrophil extracellular traps (NETs) in the pathogenesis of AOSD, and explored the effect of NETs on activati...

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Publicado en:Arthritis Res Ther
Main Authors: Hu, Qiongyi, Shi, Hui, Zeng, Ting, Liu, Honglei, Su, Yutong, Cheng, Xiaobing, Ye, Junna, Yin, Yufeng, Liu, Mengru, Zheng, Hui, Wu, Xinyao, Chi, Huihui, Zhou, Zhuochao, Jia, Jinchao, Sun, Yue, Teng, Jialin, Yang, Chengde
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323819/
https://ncbi.nlm.nih.gov/pubmed/30616678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1800-z
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