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The transcriptome landscape of the carcinogenic treatment response in the blind mole rat: insights into cancer resistance mechanisms

BACKGROUND: Spalax, the blind mole rat, developed an extraordinary cancer resistance during 40 million years of evolution in a subterranean, hypoxic, thus DNA damaging, habitat. In 50 years of Spalax research, no spontaneous cancer development has been observed. The mechanisms underlying this resist...

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Dettagli Bibliografici
Pubblicato in:BMC Genomics
Autori principali: Altwasser, Robert, Paz, Arnon, Korol, Abraham, Manov, Irena, Avivi, Aaron, Shams, Imad
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323709/
https://ncbi.nlm.nih.gov/pubmed/30621584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5417-z
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