Differential Intrasplenic Migration of Dendritic Cell Subsets Tailors Adaptive Immunity

Evidence suggests that distinct splenic dendritic cell (DC) subsets activate either CD4+ or CD8+ T cells in vivo. This bias has been partially ascribed to differential antigen presentation; however, all DC subsets can activate both T cell lineages in vitro. Therefore, we tested whether the organizat...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Calabro, Samuele, Liu, Dong, Gallman, Antonia, Nascimento, Manuela Sales L., Yu, Zizi, Zhang, Ting-ting, Chen, Pei, Zhang, Biyan, Xu, Lan, Gowthaman, Uthaman, Krishnaswamy, Jayendra Kumar, Haberman, Ann M., Williams, Adam, Eisenbarth, Stephanie C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323650/
https://ncbi.nlm.nih.gov/pubmed/27545885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.07.076
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