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Bridging channel dendritic cells induce immunity to transfused red blood cells

Red blood cell (RBC) transfusion is a life-saving therapeutic tool. However, a major complication in transfusion recipients is the generation of antibodies against non-ABO alloantigens on donor RBCs, potentially resulting in hemolysis and renal failure. Long-lived antibody responses typically requir...

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Détails bibliographiques
Publié dans:J Exp Med
Auteurs principaux: Calabro, Samuele, Gallman, Antonia, Gowthaman, Uthaman, Liu, Dong, Chen, Pei, Liu, Jingchun, Krishnaswamy, Jayendra Kumar, Nascimento, Manuela Sales L., Xu, Lan, Patel, Seema R., Williams, Adam, Tormey, Christopher A., Hod, Eldad A., Spitalnik, Steven L., Zimring, James C., Hendrickson, Jeanne E., Stowell, Sean R., Eisenbarth, Stephanie C.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886363/
https://ncbi.nlm.nih.gov/pubmed/27185856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151720
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