Extracellular Vesicles from Amnion-Derived Mesenchymal Stem Cells Ameliorate Hepatic Inflammation and Fibrosis in Rats

BACKGROUND: There are no approved drug treatments for liver fibrosis and nonalcoholic steatohepatitis (NASH), an advanced stage of fibrosis which has rapidly become a major cause of cirrhosis. Therefore, development of anti-inflammatory and antifibrotic therapies is desired. Mesenchymal stem cell- (...

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Dettagli Bibliografici
Pubblicato in:Stem Cells Int
Autori principali: Ohara, Masatsugu, Ohnishi, Shunsuke, Hosono, Hidetaka, Yamamoto, Koji, Yuyama, Kohei, Nakamura, Hideki, Fu, Qingjie, Maehara, Osamu, Suda, Goki, Sakamoto, Naoya
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2018
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323530/
https://ncbi.nlm.nih.gov/pubmed/30675167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3212643
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