Diet-dependent function of the extracellular matrix proteoglycan Lumican in obesity and glucose homeostasis

OBJECTIVE: Extracellular matrix remodeling is required for adipose expansion under increased caloric intake. In turn, inhibited expandability due to aberrant collagen deposition promotes insulin resistance and progression towards the metabolic syndrome. An emerging role for the small leucine-rich pr...

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Dettagli Bibliografici
Pubblicato in:Mol Metab
Autori principali: Wolff, G., Taranko, A.E., Meln, I., Weinmann, J., Sijmonsma, T., Lerch, S., Heide, D., Billeter, A.T., Tews, D., Krunic, D., Fischer-Posovszky, P., Müller-Stich, B.P., Herzig, S., Grimm, D., Heikenwälder, M., Kao, W.W., Vegiopoulos, A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
Soggetti:
Brief Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323191/
https://ncbi.nlm.nih.gov/pubmed/30409703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.10.007
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