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A high throughput lentivirus sieving assay identifies neutralization resistant Envelope sequences and predicts in vivo sieving

An effective prophylactic vaccine against human immunodeficiency virus (HIV) will likely require a potent antibody response that can neutralize the virus at the mucosal portal of entry. The elicitation of potent broadly-neutralizing anti-sera will be an iterative process, optimizing candidates that...

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Detalhes bibliográficos
Publicado no:J Immunol Methods
Main Authors: Iwamoto, Nami, Mason, Rosemarie, Hu, Jianfei, Ransier, Amy, Welles, Hugh, Song, Kaimei, Douek, Daniel, Roederer, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322957/
https://ncbi.nlm.nih.gov/pubmed/30389575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2018.10.013
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