RORγ regulates the NLRP3 inflammasome

RAR-related orphan receptor γ (RORγ) is a nuclear receptor that plays an essential role in the development of T helper 17 (T(h)17) cells of the adaptive immune system. The NLRP3 inflammasome is a component of the innate immune system that processes interleukin (IL)-1β into a mature cytokine. Elevate...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Billon, Cyrielle, Murray, Meghan H., Avdagic, Amer, Burris, Thomas P.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Accelerated Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322869/
https://ncbi.nlm.nih.gov/pubmed/30455347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC118.002127
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