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Spatial control of neuronal metabolism through glucose-mediated mitochondrial transport regulation

Eukaryotic cells modulate their metabolism by organizing metabolic components in response to varying nutrient availability and energy demands. In rat axons, mitochondria respond to glucose levels by halting active transport in high glucose regions. We employ quantitative modeling to explore physical...

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Publicat a:eLife
Autors principals: Agrawal, Anamika, Pekkurnaz, Gulcin, Koslover, Elena F
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322862/
https://ncbi.nlm.nih.gov/pubmed/30561333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40986
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