Recombinant IgG1 Fc hexamers block cytotoxicity and pathological changes in experimental in vitro and rat models of neuromyelitis optica

Intravenous human immunoglobulin G (IVIG) may have therapeutic benefit in neuromyelitis optica spectrum disorders (herein called NMO), in part because of the anti-inflammatory properties of the IgG Fc region. Here, we evaluated recombinant Fc hexamers consisting of the IgM μ-tailpiece fused with the...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Neuropharmacology
Asıl Yazarlar: Tradtrantip, Lukmanee, Felix, Christian M., Spirig, Rolf, Morelli, Adriana Baz, Verkman, A.S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322534/
https://ncbi.nlm.nih.gov/pubmed/29428821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.02.002
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller