Left-Biased Spermatogenic Failure in 129/SvJ Dnd1(Ter/+) Mice Correlates with Differences in Vascular Architecture, Oxygen Availability, and Metabolites(1)

Homozygosity for the Ter mutation in the RNA-binding protein Dead end 1 (Dnd1(Ter/Ter)) sensitizes germ cells to degeneration in all mouse strains. In 129/SvJ mice, approximately 10% of Dnd1(Ter/+) heterozygotes develop spermatogenic failure, and 95% of unilateral cases occur in the left testis. The...

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Detalles Bibliográficos
Publicado en:Biol Reprod
Main Authors: Bustamante-Marin, Ximena M., Cook, Matthew S., Gooding, Jessica, Newgard, Christopher, Capel, Blanche
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
Assuntos:
Testis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322448/
https://ncbi.nlm.nih.gov/pubmed/26224005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.128850
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