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129/SvJ mice have mutated CD23 and hyper IgE

CD23, the low affinity IgE receptor, is hypothesized to function as a negative regulator of IgE production. Upon discovering reduced CD23 surface levels in 129/SvJ inbred mice, we sought to further investigate 129/SvJ CD23 and to examine its influence on IgE levels. Five amino acid substitutions wer...

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Bibliografiske detaljer
Main Authors: Ford, Jill W., Sturgill, Jamie L., Conrad, Daniel H.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643045/
https://ncbi.nlm.nih.gov/pubmed/18828998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2008.08.003
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