Differences in tumor microenvironments between primary lung tumors and brain metastases in lung cancer patients: therapeutic implications for immune checkpoint inhibitors

BACKGROUND: We aimed to compare intra- and extracranial responses to immune checkpoint inhibitors (ICIs) in lung cancer with brain metastases (BM), and to explore tumor microenvironments of the brain and lungs focusing on the programmed cell death-1 (PD-1)/programmed cell death ligand-1 (PD-L1) path...

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Dades bibliogràfiques
Publicat a:BMC Cancer
Autors principals: Kim, Ryul, Keam, Bhumsuk, Kim, Sehui, Kim, Miso, Kim, Se Hyun, Kim, Jin Wook, Kim, Yu Jung, Kim, Tae Min, Jeon, Yoon Kyung, Kim, Dong-Wan, Chung, Doo Hyun, Lee, Jong Seok, Heo, Dae Seog
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322302/
https://ncbi.nlm.nih.gov/pubmed/30616523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-5214-8
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