Differences in tumor microenvironments between primary lung tumors and brain metastases in lung cancer patients: therapeutic implications for immune checkpoint inhibitors

BACKGROUND: We aimed to compare intra- and extracranial responses to immune checkpoint inhibitors (ICIs) in lung cancer with brain metastases (BM), and to explore tumor microenvironments of the brain and lungs focusing on the programmed cell death-1 (PD-1)/programmed cell death ligand-1 (PD-L1) path...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Kim, Ryul, Keam, Bhumsuk, Kim, Sehui, Kim, Miso, Kim, Se Hyun, Kim, Jin Wook, Kim, Yu Jung, Kim, Tae Min, Jeon, Yoon Kyung, Kim, Dong-Wan, Chung, Doo Hyun, Lee, Jong Seok, Heo, Dae Seog
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322302/
https://ncbi.nlm.nih.gov/pubmed/30616523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-5214-8
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