Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis

BACKGROUND: The Slug-E-cadherin axis plays a critical role in non-small-cell lung cancers (NSCLCs) where aberrant upregulation of Slug promotes cancer metastasis. Now, the post-translational modifications of Slug and their regulation mechanisms still remain unclear in lung cancer. Hence, exploring t...

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Bibliografski detalji
Izdano u:J Exp Clin Cancer Res
Glavni autori: Hung, Pei-Fang, Hong, Tse-Ming, Chang, Che-Chang, Hung, Chung-Lieh, Hsu, Yuan-Ling, Chang, Yih-Leong, Wu, Chen-Tu, Chang, Gee-Chen, Chan, Nei-Li, Yu, Sung-Liang, Yang, Pan-Chyr, Pan, Szu-Hua
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322271/
https://ncbi.nlm.nih.gov/pubmed/30612578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0996-8
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