MDA-9/Syntenin-Slug transcriptional complex promote epithelial-mesenchymal transition and invasion/metastasis in lung adenocarcinoma

Melanoma differentiation-associated gene-9 (MDA-9)/Syntenin is a novel therapeutic target because it plays critical roles in cancer progression and exosome biogenesis. Here we show that Slug, a key epithelial-mesenchymal-transition (EMT) regulator, is a MDA-9/Syntenin downstream target. Mitogen EGF...

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Publicat a:Oncotarget
Autors principals: Wang, Lu-Kai, Pan, Szu-Hua, Chang, Yih-Leong, Hung, Pei-Fang, Kao, Shih-Han, Wang, Wen-Lung, Lin, Ching-Wen, Yang, Shuenn-Chen, Liang, Chen-Hsien, Wu, Chen-Tu, Hsiao, Tzu-Hung, Hong, Tse-Ming, Yang, Pan-Chyr
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808006/
https://ncbi.nlm.nih.gov/pubmed/26561205
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