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Phosphorylation of LCRMP-1 by GSK3β Promotes Filopoda Formation, Migration and Invasion Abilities in Lung Cancer Cells

LCRMP-1, a novel isoform of CRMP-1, can promote cancer cell migration, invasion and associate with poor clinical outcome in patients with non-small-cell lung cancer (NSCLC). However, the underlying regulatory mechanisms of LCRMP-1 in cancer cell invasiveness still remain obscure. Here, we report tha...

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Autors principals: Wang, Wen-Lung, Hong, Tse-Ming, Chang, Yih-Leong, Wu, Chen-Tu, Pan, Szu-Hua, Yang, Pan-Chyr
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283678/
https://ncbi.nlm.nih.gov/pubmed/22363707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031689
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