Loss of intestinal sympathetic innervation elicits an innate immune driven colitis

BACKGROUND: Both the parasympathetic and sympathetic nervous system exert control over innate immune responses. In inflammatory bowel disease, sympathetic innervation in intestinal mucosa is reduced. Our aim was to investigate the role of sympathetic innervation to the intestine on regulation of the...

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Udgivet i:Mol Med
Main Authors: Willemze, Rose A., Welting, Olaf, van Hamersveld, Patricia, Verseijden, Caroline, Nijhuis, Laurens E., Hilbers, Francisca W., Meijer, Sybren L., Heesters, Balthasar A., Folgering, Joost H. A., Darwinkel, Harold, Blancou, Philippe, Vervoordeldonk, Margriet J., Seppen, Jurgen, Heinsbroek, Sigrid E. M., de Jonge, Wouter J.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322236/
https://ncbi.nlm.nih.gov/pubmed/30616543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0068-8
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